If you’re wondering why people don’t care about their appearance, IDK. Probably many reasons, one of which might be that they’re concerned about more important things than how they look to other people; however, sometimes those “more important” things are depression & anxiety. If you’re concerned about someone in particular, if the opportunity presents itself, ask them how they’re doing. Sometimes, just an expression of concern can really brighten someone’s day. (I hope I’ve understood your question correctly!)